Point: Oral Hypoglycemic Agents Should Not Be Used to Treat Diabetic Pregnant Women
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Point: Oral hypoglycemic agents should not be used to treat diabetic pregnant women.
Not Be Used to Treat Diabetic Pregnant Women S tudies in pregnancy indicate that the most important glucose concentration throughout the day is the peak postprandial glucose response; i.e., it is the highest blood glucose of the day, not the average, that predicts risk of untoward effects. The Diabetes in Early Pregnancy (DIEP) Study was a multicenter, casecontrolled trial of type 1 diabetic wo...
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Should Be Used to Treat Diabetic Pregnant Women I t has now been established that even mild forms of gestational diabetes mellitus (GDM) (impaired glucose tolerance according to World Health Organization 1985 criteria) can cause major morbidity and even mortality if left untreated (1). As with type 2 diabetes, the prevalence of GDM has increased dramatically, linked to the worldwide obesity epi...
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Unsurprisingly, a recent comparison of important international guidelines found conflicting advice about antihistamines, reflecting the uncertainty in international clinical practice: a US guideline recommends the use of diphenhydramine as second line treatment in anaphylaxis; evidence for this recommendation is graded as "expert opinion/ extrapolated from higher order evidence. DRUG INFORMATIO...
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I t is well established that folate requirements increase during pregnancy and that supplementing 0.4 mg folic acid/ day to the general pregnant population is beneficial in terms of reducing the risk of neural tube defects (NTDs). Offspring of women with pregestational diabetes mellitus have an increased risk of congenital anomalies, including NTDs (1). In animal models, folic acid supplementat...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2007
ISSN: 0149-5992,1935-5548
DOI: 10.2337/dc07-1282